The first is what would happen if you have a pseudoallergic reaction to codeine. In this case, a doctor would most likely prescribe you a stronger opioid, because stronger opioids tend to have less noticeable histamine reactions. If you are truly allergic to codeine, you will have to be given a pain reliever from a different class of medications, because you are likely allergic to all opioid medicines. To sum up, is a codeine allergy possible?
Ask your doctor how to avoid withdrawal symptoms when you stop using codeine. Store at room temperature away from moisture and heat. Keep track of the amount of medicine used from each new bottle. Codeine is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription. After you have stopped using this medication, flush any unused pills down the toilet.
What happens if I miss a dose? Since codeine is taken as needed, you may not be on a dosing schedule. If you are taking the medication regularly, take the missed dose as soon as you remember. There is growing evidence that numerous drug-induced allergies are not mediated by the pathogenic role of allergen-specific immunoglobulin E IgE. The case for such non—IgE-mediated, or pseudoallergic, reactions is proposed on the basis of the mechanism of mast cell and basophil activation.
The pseudoallergic symptoms can resemble those of a true allergy but are caused by histamine release from cutaneous mast cells. Oral and injectable opioids are among the drugs that cause these symptoms, but the symptoms may not be due to a true allergy.
Therefore, in patients who show these reactions, it is important to choose a safe alternative drug. Remember that most patients who say they are allergic to an opioid have experienced only a side effect that has been misclassified as an allergy. Published data suggest that as many as nine out of 10 patients labeled with an opioid allergy do not have a true allergy. This article briefly discusses the true opioid allergy versus pseudoallergy, opioid side effects, and alternative options to control pain.
Allergy Symptoms All opioids, particularly the naturally occurring and semisynthetic compounds, cause allergic reactions. Codeine, morphine, and meperidine are the main opioids that cause most allergic-type reactions. Although some of the symptoms resemble those of a true allergy, they are in reality symptoms of pseudoallergies caused by endogenous histamine release from the mast cells, which is also considered a pharmacological effect. These symptoms include flushing, itching, sneezing, hives, sweating, exacerbation of asthma, and low blood pressure, and their occurrence depends on the concentration of opioids in the mast cells.
A true allergy to opioids is rare and seems to be IgE mediated or T-cell mediated. Symptoms of a true opioid allergy include hives, maculopapular rash, erythema multiforme, pustular rash, severe hypotension, bronchospasm, and angioedema. They are as follows: I was taking for my back injury All the best hope that helps 5 years ago Hello and welcome Julia.
I have been on both of these for over 5 years, along with other long acting pain meds. I have had no trouble with either drug at all. However that's just me. We are all different of course. I would doubt very much that codeine would actually cause asthma. Codeine side effects Get emergency medical help if you have signs of an allergic reaction to codeine: Like other narcotic medicines, codeine can slow your breathing.
Death may occur if breathing becomes too weak. A person caring for you should seek emergency medical attention if you have slow breathing with long pauses, blue colored lips, or if you are hard to wake up. Call your doctor at once if you have: Seek medical attention right away if you have symptoms of serotonin syndrome, such as: Serious side effects may be more likely in older adults and those who are overweight , malnourished, or debilitated.
Long-term use of opioid medication may affect fertility ability to have children in men or women. It is not known whether opioid effects on fertility are permanent. Common codeine side effects include:
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