Apo metoprolol tartrate 25 mg
Their instructions may be different to the information in this leaflet. How much to take Your doctor will tell you how much of this medicine you should take.
This will depend on your condition and whether you are taking any other medicines. Do not stop taking your medicine or change your dosage without first checking with your doctor.
The usual dose is from 50 mg to mg each day, either as a single dose or divided into two doses. The usual dose is from mg to mg each day, divided into two or three doses. After a heart attack: The usual dose is mg each day, divided into two doses. The usual dose is from mg to mg each day, divided into two doses morning and evening.
How to take it Swallow the tablets whole with a full glass of water. It does not matter if you take metoprolol before or after food. How long to take it Continue taking metoprolol for as long as your doctor tells you.
Metoprolol helps to control your symptoms but it does not cure your condition. To reduce your risk of side effects, your doctor may direct you to start this medication at a low dose and gradually increase your dose.
Follow your doctor's instructions carefully. Use this medication regularly to get the most benefit from it. To help you remember, take it at the same time s each day. Dosage should be adjusted based on patient response. The minimum available dose is one half of the 25 mg tablet. Dosage should be adjusted according to blood pressure response. What other drugs will affect metoprolol? When discontinuing chronically administered metoprolol, particularly in patients with coronary artery disease, the dosage should be gradually reduced over a period of 1 to 2 weeks and the patient should be carefully monitored.
If angina markedly worsens or acute coronary insufficiency develops, metoprolol administration should be reinstated promptly, at least temporarily, and other measures appropriate for the management of unstable angina should be taken.
Because coronary artery disease is common and may be unrecognized, it may be prudent not to discontinue metoprolol therapy abruptly even in patients treated only for hypertension. Use During Major Surgery Chronically administered beta-blocking therapy should not be routinely withdrawn prior to major surgery; however, the impaired ability of the heart to respond to reflex adrenergic stimuli may augment the risks of general anesthesia and surgical procedures. Bradycardia Bradycardia, including sinus pause, heart block, and cardiac arrest have occurred with the use of metoprolol.
Patients with first-degree atrioventricular block, sinus node dysfunction, or conduction disorders may be at increased risk. Monitor heart rate and rhythm in patients receiving metoprolol. If severe bradycardia develops, reduce or stop metoprolol.
Exacerbation of Bronchospastic Disease Patients with bronchospastic disease, should, in general, not receive beta-blockers, including metoprolol.
Because of its relative beta1 selectivity, however, metoprolol may be used in patients with bronchospastic disease who do not respond to, or cannot tolerate, other antihypertensive treatment. Bronchodilators, including beta2 agonists, should be readily available or administered concomitantly.
Diabetes and Hypoglycemia Beta-blockers may mask tachycardia occurring with hypoglycemia, but other manifestations such as dizziness and sweating may not be significantly affected. Pheochromocytoma If metoprolol is used in the setting of pheochromocytoma, it should be given in combination with an alpha-blocker, and only after the alpha-blocker has been initiated.
Retrieved 22 April Carlsson, edited by Bo Technological systems and industrial dynamics. Archived PDF from the original on 23 April Archived from the original on 22 March
Metoprolol
Calcium Channel Blockers Concomitant administration of a beta-adrenergic antagonist with a calcium channel blocker may produce an additive reduction in myocardial contractility because of negative chronotropic and inotropic effects. All medicines can have side effects. If a dose should be missed, the patient should take only the next scheduled dose without doubling it. Dosage should be adjusted based metoprolol patient response. You also may experience discomfort or pain in your chest while taking the drug. Metoprolol tartrate showed effects on spermatogenesis in male rats at a therapeutic dose level, but had no effect on rates of conception at higher doses in animal fertility studies see Carcinogenesis, Mutagenesis, Impairment of Fertility. Diabetes and Hypoglycemia Beta blockers may mask tachycardia occurring with hypoglycemia, but other manifestations such as dizziness apo sweating may not be significantly affected. Myocardial Infarction The precise mechanism of action of metoprolol tartrate in patients with suspected or definite myocardial infarction is not known. Take this medication by mouthwith or right after a meal, as directed by your doctor, usually times a day, apo metoprolol tartrate 25 mg. This medication is also used to treat chest pain angina and to improve survival after a heart tartrate. Pediatric Use Safety and effectiveness in pediatric patients have not been established.
Metoprolol Side Effects
Nonetheless, because the overall regimen showed a clear beneficial effect on survival metoprolol evidence of an early adverse effect metoprolol tartrate, one acceptable dosage regimen is the precise regimen used in the trial. Because of its relative beta1 selectivity, however, metoprolol may be used in patients with bronchospastic disease who do not respond to, apo metoprolol tartrate 25 mg, or cannot tolerate, other antihypertensive treatment. In worldwide clinical trials of metoprolol in myocardial infarction, where approximately patients were over 65 years of age 0 over 75 years of ageno age related differences in safety and effectiveness were found. Ischemic Heart Disease Do not abruptly discontinue metoprolol tartrate therapy in patients with coronary artery disease. Ischemic Heart Disease Do not abruptly discontinue metoprolol apo in patients with coronary artery disease. Nursing Mothers Metoprolol tartrate is excreted in breast milk in a very small quantity. If a dose should be missed, the patient should take only the next scheduled dose without doubling it. Symptoms of an overdose may include feeling sick and vomiting, apo tartrate and nails, very low blood pressure, slow heart beat, difficulty breathing, fainting, convulsions fitscoma or death. However, antihypertensive activity does not appear to be related to plasma levels.
Metoprolol Tartrate
Metoprolol Tartrate vs. Metoprolol Succinate: What’s the Difference?
Use During Major Surgery Chronically administered beta-blocking therapy should not be routinely apo prior to major surgery; however, the impaired ability of the heart to respond to reflex adrenergic stimuli may augment the risks of general anesthesia and surgical procedures. Digitalis Glycosides and Beta-Blockers Both digitalis glycosides and beta-blockers slow atrioventricular conduction and decrease heart rate. Pharmacodynamics Relative beta1 selectivity is demonstrated by the following: However, greater sensitivity of some elderly individuals taking metoprolol tartrate cannot be categorically ruled out, apo metoprolol tartrate 25 mg. Rebound hypertension that can follow withdrawal of clonidine may be increased in patients receiving concurrent beta-blocker treatment. Therefore, in general, it is recommended that dosing proceed with caution in this population. Heart Problems Because metoprolol 25 mg works to change your heart rate, it can cause metoprolol serious side effects in how your heart beats. The dosage is based on your tartrate condition and tartrate to treatment. Use this medication regularly to get the most benefit from it. The FDA categorizes medications based on safety for use during pregnancy, apo metoprolol tartrate 25 mg. Phenergan help with nausea doses were associated with some maternal toxicity, and growth delay of the offspring in utero, which was reflected in minimally lower weights at birth. Calcium Channel Blockers Concomitant administration of a beta-adrenergic antagonist with a calcium channel blocker apo produce an metoprolol reduction in myocardial contractility because of negative chronotropic and inotropic effects. Alpha-Adrenergic Agents Antihypertensive effect of alpha-adrenergic blockers such as guanethidine, betanidine, apo metoprolol tartrate 25 mg, reserpine, alpha-methyldopa or clonidine may be potentiated by beta-blockers including metoprolol. Other reported clinical experience in elderly hypertensive patients has not identified any difference in response from younger patients.
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