This job allowed me to live! I don't want to become dependent on it, so I started tapering. My goal to go off this drug completely and use it only for emergencies.

I take it as needed, usually 1mg every three days at night. Sleep like a baby and wake up the next morning energised and ready to start the day. Only worry is the possible addictive qualities. I also take small dose Cymbalta 30mg, each morning. Have been contemplating weaning off this and introducing Ativan every evening. Over time you will build a tolerance for the drug. And getting off of it can be difficult. If you are taking high doses, like more than 3 mg and you quite cold turkey, you can die.

So you have to step down from it little by little. You may experience withdrawal symptoms while stepping down that include insomnia and anxiety attacks. But if you step down slowly enough and get the help of a doctor with Gaba meds to support you, you may not have such serious withdrawal. I suggest this drug only be taken in serious emergencies and be taken for no more than 3 days before starting to step down.

This is true for all Benzodiazepine drugs. Take the least mg dosage you need try to stay under 4 mg in a 24 hour period. And after as little as 3 days, try to lower your dosage. Lorazepam should never be shared with another person, especially someone who has a history of drug abuse or addiction. Keep the medication in a secure place where others cannot get to it. Contact your doctor if this medicine seems to stop working as well in treating your symptoms.

Do not stop using lorazepam suddenly without first talking to your doctor. You may need to use less and less before you stop the medication completely. Your symptoms may return when you stop using lorazepam after using it over a long period of time. You may also have seizures or withdrawal symptoms when you stop using lorazepam.

Withdrawal symptoms may include tremor, sweating, muscle cramps , stomach pain, vomiting, unusual thoughts or behavior, and seizure convulsions. To be sure this medication is not causing harmful effects, your doctor may need to check your progress on a regular basis. Do not miss any scheduled visits to your doctor. Store lorazepam at room temperature away from moisture, heat, and light. Store the liquid form of lorazepam in the refrigerator. Keep track of how many pills have been used from each new bottle of this medicine.

Benzodiazepines are drugs of abuse and you should be aware if any person in the household is using this medicine improperly or without a prescription. Drug and alcohol dependence — The risk of abuse of lorazepam is increased in dependent patients. Higher doses and longer periods of use increase the risk of developing a benzodiazepine dependence. Potent benzodiazepines, such as lorazepam, alprazolam , and triazolam , have the highest risk of causing a dependence.

This is desirable with amnesic and sedative effects but undesirable with anxiolytic, hypnotic, and anticonvulsant effects. Patients initially experience drastic relief from anxiety and sleeplessness, but symptoms gradually return, relatively soon in the case of insomnia, but more slowly in the case of anxiety symptoms. After four to six months of regular benzodiazepine use, evidence of continued efficacy declines. If regular treatment is continued for longer than four to six months, dose increases may be necessary to maintain effects, but treatment-resistant symptoms may in fact be benzodiazepine withdrawal symptoms.

Increasing the dose may overcome tolerance, but tolerance may then develop to the higher dose and adverse effects may persist and worsen. The mechanism of tolerance to benzodiazepines is complex and involves GABAA receptor downregulation, alterations to subunit configuration of GABAA receptors, uncoupling and internalisation of the benzodiazepine binding site from the GABAA receptor complex as well as changes in gene expression.

Lorazepam's relatively short serum half-life, its confinement mainly to the vascular space, and its inactive metabolite can result in interdose withdrawal phenomena and next-dose cravings, that may reinforce psychological dependence. Because of its high potency, the smallest lorazepam tablet strength of 0. If any benzodiazepine has been used long-term, the recommendation is a gradual dose taper over a period of weeks, months or longer, according to dose and duration of use, the degree of dependence and the individual.

Coming off long-term lorazepam use may be more realistically achieved by a gradual switch to an equivalent dose of diazepam and a period of stabilization on this, and only then initiating dose reductions.

The advantage of switching to diazepam is that dose reductions are felt less acutely, because of the longer half-lives 20— hours of diazepam and its active metabolites. Lorazepam, as with other benzodiazepine drugs, can cause physical dependence , addiction , and benzodiazepine withdrawal syndrome. The higher the dose and the longer the drug is taken, the greater the risk of experiencing unpleasant withdrawal symptoms.

Withdrawal symptoms can, however, occur from standard dosages and also after short-term use. Benzodiazepine treatment should be discontinued as soon as possible via a slow and gradual dose reduction regimen. Withdrawal symptoms can range from mild anxiety and insomnia to more severe symptoms such as seizures and psychosis.

The risk and severity of withdrawal are increased with long-term use, use of high doses, abrupt or over-rapid reduction, among other factors. Short-acting benzodiazepines such as lorazepam are more likely to cause a more severe withdrawal syndrome compared to longer-acting benzodiazepines. It takes about 18—36 hours for the benzodiazepine to be removed from the body. Interactions[ edit ] Lorazepam is not usually fatal in overdose, but may cause fatal respiratory depression if taken in overdose with alcohol.

The combination also causes synergistic enhancement of the disinhibitory and amnesic effects of both drugs, with potentially embarrassing or criminal consequences. Some experts advise that patients should be warned against drinking alcohol while on lorazepam treatment, [28] [65] but such clear warnings are not universal.

Some antidepressants, antiepileptic drugs such as phenobarbital, phenytoin and carbamazepine, sedative antihistamines, opiates, antipsychotics and alcohol, when taken with lorazepam may result in enhanced sedative effects.

Benzodiazepine overdose In cases of a suspected lorazepam overdose, it is important to establish whether the patient is a regular user of lorazepam or other benzodiazepines since regular use causes tolerance to develop.

Possible side effects In addition to its desired action, this medication may cause some side effects, notably: Each person may react differently to a treatment. If you think this medication may be causing side effects including those described here, or others , talk to your doctor or pharmacist. He or she can help you to determine whether or not the medication is the source of the problem. Storage information As with most medications, this product should be stored at room temperature.

Store it in a secure location where it will not be exposed to excessive heat, moisture or direct sunlight.

lorazepam (oral) (Ativan)

Patients should not be discharged from the hospital within 24 hours of receiving lorazepam premedication unless accompanied by a caregiver. The risk and severity of withdrawal are increased with long-term use, use of high doses, abrupt or over-rapid reduction, among 5mg factors. Store the liquid form of lorazepam apo the refrigerator. This medication may be taken with or without food, apo lorazepam 5mg. In the US, the FDA advises against use of benzodiazepines such as lorazepam for longer than four weeks. Do not oxycodone addiction and depression lorazepam without your doctor's consent if you are pregnant. Allergy or hypersensitivity — Past hypersensitivity or allergy to lorazepam, to any benzodiazepine, or to any of the ingredients in lorazepam tablets or injections Severe respiratory failure — Benzodiazepines, including lorazepam, may depress central nervous system respiratory drive and are contraindicated in severe respiratory failure. Ive been going to doctors ever since staying clean not seeking meds on the streets. Falls and hip fractures are frequently reported. Adverse effects are more common in the elderly, and they appear at lower doses than in younger patients. To be sure this medication is not lorazepam harmful effects, your doctor may need to check your progress on a regular basis.

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