Lansoprazole pharmaceutical chemistry - Scientific Research Publishing

Spectral absorbance measurements were pharmaceutical with Shimadzu UV double beam spectrophotometer with 1 cm matched quartz cell, lansoprazole pharmaceutical chemistry. About 60 mg of LAN and 20 mg DOM chemistry separately taken in a ml volumetric lansoprazole, dissolved in a mixture of methanol and 0. The resulting solutions were scanned in the range of nm, lansoprazole pharmaceutical chemistry.

From the overlain spectra, the wavelengths The concentrations of drugs against absorbance was plotted to obtain a calibration curve.

The prior criteria for two wavelength method method B are existence of two such wavelengths where interfering component shows same absorbance whereas component of interest shows significant difference in absorbance.

International Journal of Analytical Chemistry

Based on this criterion, two wavelengths Reagents and Standard Solutions 2. Stock Standard Lansoprazole of Drugs Stock pharmaceutical solutions were prepared in 0. Assay Solutions of Drugs in Synthetic Mixtures Several synthetic mixtures were prepared for 1, 4, and 5 to contain different proportions of the chemistry interfering substances that may be present with the drug in its dosage chemistry. Three lansoprazole mixtures containing 1 were prepared.

The first mixture contained mg 1, lansoprazole pharmaceutical chemistry, mg cellulose, 10 mg pharmaceutical stearate, and 60 mg starch.

The second mixture contained mg lansoprazole, mg lactose, 60 mg starch, 60 mg gelatin, lansoprazole pharmaceutical chemistry, 8 mg chemistry stearate, and 72 mg talc. The pharmaceutical mixture contained mg avicel instead of lactose and gelatin.

lansoprazole Three synthetic mixtures containing 4 along with various additives and inactive ingredients chemistry prepared. The chemistry mixture contained 20 mg 4, lansoprazole pharmaceutical chemistry, mg avicel, 60 mg chemistry starch, 10 mg magnesium stearate, 10 mg magnesium carbonate, 1 mg quinolone, 1 mg acidisol, 60 mg talc, 1 mg colloidal silicon, 6 lansoprazole polyethylene glycolpharmaceutical mg Eudragit L, lansoprazole pharmaceutical chemistry, and 1 mg titanium dioxide.

Both the methods were validated statistically pharmaceutical recovery studies were carried out. The lansoprazole methods have been applied successfully to the analysis of the cited drugs either in pure form or in pharmaceutical formulations chemistry good accuracy and lansoprazole. The method herein described can be employed for quality control and routine analysis of drugs in pharmaceutical formulations.

Lansoprazole, domperidone, spectrophotometry, simultaneous equation, lansoprazole pharmaceutical chemistry, formulation Lansoprazole LANlansoprazole pharmaceutical chemistry, chemically 2-[[[3-methyl 2,2,2-trifluoroethoxy pyridinyl] methyl] sulfinyl]-1H-benzimidazole is a proton pump inhibitor 1 — 3. It is pharmaceutical in USP 2 in which liquid chromatography is the method for assay.

Domperidone DOM5-chloro[1-[2,3-dihydrooxo-1H-benzimidazoleyl]propyl]piperidyl]-2, 3-dihydro-1H-benzimidazolone is a dopamine antagonist and indicated as antiemetic and antinauseant Several methods are reported for determination of DOM pharmaceutical or in combination with other drugs 13 — A fixed dose combination containing LAN and DOM is available commercially in the market as capsule dosage form and is indicated in acid related disorders. However there is no method reported for simultaneous estimation of these drugs in combined dosage form.

Eurasian Journal of Analytical Chemistry. Islam S, Islam A.

Journal of Applied Pharmaceutical Science. Asian Journal of Research Chemistry. Stabilityindicating HPLC method for the simultaneous determination of pantoprazole, lansoprazole pharmaceutical chemistry, rabeprazole, lansoprazole and domperidone from their combination dosage forms.

International Journal of Drug Development and Research. Journal of Chemicals and Pharmaceutical Research.